{"id":128303,"date":"2025-05-21T16:41:37","date_gmt":"2025-05-21T15:41:37","guid":{"rendered":"https:\/\/easo.org\/?p=128303"},"modified":"2025-05-21T16:45:59","modified_gmt":"2025-05-21T15:45:59","slug":"spotlight-meet-ecn-member-teona-nutsubidze","status":"publish","type":"post","link":"https:\/\/easo.org\/fr\/spotlight-meet-ecn-member-teona-nutsubidze\/","title":{"rendered":"Pleins feux sur : Rencontre avec Teona Nutsubidze, membre de l'ECN"},"content":{"rendered":"

Je me pr\u00e9sente bri\u00e8vement : je m'appelle Teona Nutsubidze et je suis endocrinologue. Je travaille \u00e0 l'Institut national d'endocrinologie de G\u00e9orgie et je pr\u00e9pare un doctorat \u00e0 l'universit\u00e9 d'\u00c9tat de Tbilissi.<\/em><\/p>\n

Concilier pratique clinique et recherche pr\u00e9sente \u00e0 la fois des d\u00e9fis et des avantages. \u00c0 ce stade de ma carri\u00e8re, la plateforme ECN offre une occasion unique d'apprendre et d'\u00e9voluer aux c\u00f4t\u00e9s d'autres personnes tout aussi passionn\u00e9es. Je suis ravie de faire partie de ce r\u00e9seau inspirant.<\/em><\/p>\n

Mon parcours dans la recherche sur l'ob\u00e9sit\u00e9 infantile et la nutrition<\/h3>\n

Au cours de mon stage en endocrinologie, j'ai suivi ma mentor, le professeur Elena Giorgadze, fondatrice de l'Institut national g\u00e9orgien d'endocrinologie.<\/p>\n

Nous avons rencontr\u00e9 un cas qui a profond\u00e9ment influenc\u00e9 ma vision de la sant\u00e9 m\u00e9tabolique \u00e0 diff\u00e9rentes \u00e9tapes de la vie.<\/p>\n

Une fillette de six ans souffrant d'ob\u00e9sit\u00e9 et pr\u00e9sentant des signes de pubert\u00e9 pr\u00e9coce, tr\u00e8s inhabituels pour une enfant de son \u00e2ge, a \u00e9t\u00e9 examin\u00e9e par le professeur Giorgadze. Il n'y avait aucune cause \u00e9vidente \u00e0 l'activation pr\u00e9matur\u00e9e de son axe hypothalamo-hypophyso-surr\u00e9nalien, mais son corps m\u00fbrissait pr\u00e9matur\u00e9ment.<\/p>\n

Au d\u00e9part, il n'y avait qu'un seul cas, mais peu apr\u00e8s, un autre cas pr\u00e9sentant des complications similaires est apparu. Pendant la pand\u00e9mie de COVID-19, j'ai commenc\u00e9 \u00e0 voir de plus en plus de cas pr\u00e9sentant un sch\u00e9ma inqui\u00e9tant : des jeunes filles en surpoids qui atteignaient \u00e9galement la pubert\u00e9 plus t\u00f4t que pr\u00e9vu. Il ne s'agissait pas seulement d'un probl\u00e8me m\u00e9dical, mais d'une lutte profond\u00e9ment personnelle. Ces enfants \u00e9taient non seulement confront\u00e9s au risque de futurs probl\u00e8mes m\u00e9taboliques, mais aussi au poids des jugements, des commentaires chuchot\u00e9s et de l'exclusion, ce qui les amenait \u00e0 avoir honte de changements sur lesquels ils n'avaient aucun contr\u00f4le \u2013 un lourd fardeau social \u00e0 porter \u00e0 un si jeune \u00e2ge.<\/p>\n

Je m'int\u00e9resse de plus en plus \u00e0 la mani\u00e8re dont la sant\u00e9 m\u00e9tabolique pendant l'enfance influence les r\u00e9sultats endocriniens \u00e0 long terme. Si la g\u00e9n\u00e9tique et le poids jouent un r\u00f4le, la question cl\u00e9 est la suivante : dans quelle mesure l'alimentation a-t-elle r\u00e9ellement un impact sur ce ph\u00e9nom\u00e8ne ? S'agit-il uniquement d'un exc\u00e8s de calories ou la qualit\u00e9 des aliments a-t-elle une influence plus importante ? Nous ne pouvons pas modifier la g\u00e9n\u00e9tique, mais en nous concentrant sur la qualit\u00e9 et la pr\u00e9paration des aliments plut\u00f4t que sur la simple r\u00e9duction des calories, nous pourrions consid\u00e9rablement remodeler les strat\u00e9gies nutritionnelles pendant l'enfance.<\/p>\n

\"A<\/p>\n

D\u00e9termin\u00e9 \u00e0 trouver des r\u00e9ponses, j'ai commenc\u00e9 mon doctorat en 2024. Nos recherches examinent comment les r\u00e9gimes riches en aliments transform\u00e9s, principalement ceux courants dans les habitudes alimentaires occidentales, contribuent \u00e0 une consommation \u00e9lev\u00e9e de produits finaux de glycation avanc\u00e9e (AGE), en se concentrant sp\u00e9cifiquement sur la carboxym\u00e9thyl-lysine (CML). Mon \u00e9quipe a r\u00e9cemment publi\u00e9 notre premier article sur le sujet : https:\/\/doi.org\/10.52340\/spectri.2024.09.01.01<\/a>.<\/p>\n

Nous nous concentrons principalement sur les ann\u00e9es pr\u00e9pub\u00e8res (6 \u00e0 9 ans), p\u00e9riode durant laquelle les enfants acqui\u00e8rent des habitudes alimentaires ind\u00e9pendantes. Afin d'approfondir nos connaissances, la prochaine phase de notre recherche vise \u00e0 d\u00e9terminer si la consommation d'AGE provenant d'aliments ultra-transform\u00e9s (AUT) contribue de mani\u00e8re significative \u00e0 l'apport alimentaire global ou si son impact est relativement mineur par rapport \u00e0 d'autres sources alimentaires.<\/p>\n

Si l'alimentation des enfants a fait l'objet d'\u00e9tudes approfondies dans certaines r\u00e9gions du monde, on dispose de beaucoup moins de donn\u00e9es sur la G\u00e9orgie et les r\u00e9gions voisines. Cette lacune rend plus difficile la compr\u00e9hension des habitudes alimentaires locales et l'\u00e9laboration d'interventions nutritionnelles efficaces.<\/p>\n

En mars 2025, notre petite \u00e9quipe d\u00e9vou\u00e9e lancera la premi\u00e8re \u00e9tude alimentaire en G\u00e9orgie portant sur 500 enfants \u00e2g\u00e9s de 6 \u00e0 9 ans. Cette \u00e9tude jettera les bases d'\u00e9valuations alimentaires r\u00e9gionales en analysant les aliments les plus couramment consomm\u00e9s, les techniques de cuisson et l'apport alimentaire en produits finaux de glycation avanc\u00e9e (dAGE). Elle comprendra un rappel alimentaire sur 24 heures \u00e0 l'aide d'entretiens en face \u00e0 face sur papier et d'un questionnaire AGE Quick Score adapt\u00e9. (Uribarri et al. (2010b))<\/a> pour estimer l'exposition aux dAGE, affin\u00e9e afin de mieux refl\u00e9ter la culture alimentaire et les techniques de pr\u00e9paration g\u00e9orgiennes. Cet effort s'appuie sur les travaux d'une \u00e9quipe de recherche pionni\u00e8re, avec les conseils particuliers du professeur Jaime Uribarri, contributeur cl\u00e9 \u00e0 la base de donn\u00e9es sur les AGE alimentaires la plus largement utilis\u00e9e, dont l'expertise garantit l'exactitude et la pertinence culturelle du questionnaire.<\/p>\n

Le recrutement se fera par le biais de cliniques et des r\u00e9seaux sociaux, afin de garantir un \u00e9chantillon repr\u00e9sentatif. Cette \u00e9tude se caract\u00e9rise principalement par l'accent mis sur la sensibilisation \u00e0 la nutrition. Les familles b\u00e9n\u00e9ficieront d'un accompagnement personnalis\u00e9 pour la planification des repas et de conseils di\u00e9t\u00e9tiques afin de promouvoir des habitudes alimentaires plus saines.<\/p>\n

Nous recherchons activement des chercheurs et des scientifiques partageant notre enthousiasme pour la nutrition p\u00e9diatrique et la sant\u00e9 hormonale. Si vous \u00eates int\u00e9ress\u00e9 par une collaboration ou si vous avez men\u00e9 une \u00e9tude similaire et souhaitez partager votre exp\u00e9rience, n'h\u00e9sitez pas \u00e0 nous contacter. Nous serions ravis de vous rencontrer.<\/p>\n

J'ai une mission<\/h3>\n

Comprendre comment le poids et la nutrition influencent la sant\u00e9 m\u00e9tabolique et le moment de la pubert\u00e9 n'est pas seulement un objectif de recherche ; c'est une v\u00e9ritable mission pour moi. Je sais que cela peut sembler un peu ambitieux, alors laissez-moi vous expliquer.<\/p>\n

La recherche universitaire est une qu\u00eate profond\u00e9ment personnelle. Chaque d\u00e9couverte nous rapproche de notre objectif : am\u00e9liorer la vie des gens et les soins prodigu\u00e9s aux patients, que ce soit en tant que professionnels de sant\u00e9, scientifiques, enseignants ou d\u00e9fenseurs.<\/p>\n

Au-del\u00e0 de mon r\u00f4le de clinicien et de chercheur, je suis \u00e9galement un patient. En tant que survivant du cancer, je comprends l'urgence, l'espoir et les d\u00e9fis qui accompagnent la lutte contre la maladie. Mon parcours, qui comprend une greffe de cellules souches r\u00e9ussie le 15 avril 2018, jour que je c\u00e9l\u00e8bre d\u00e9sormais comme mon deuxi\u00e8me anniversaire, a fa\u00e7onn\u00e9 mon engagement envers la recherche qui compte vraiment pour les patients. Cette exp\u00e9rience alimente ma d\u00e9termination \u00e0 combler le foss\u00e9 entre la science et son impact dans le monde r\u00e9el, en veillant \u00e0 ce que chaque d\u00e9couverte m\u00e8ne \u00e0 un changement significatif pour ceux qui en ont le plus besoin.<\/p>\n

Je serais ravi d'avoir de vos nouvelles si vous souhaitez entrer en contact, collaborer ou \u00e9changer des id\u00e9es. Travaillons ensemble pour faire la diff\u00e9rence.<\/p>\n

Courriel :<\/strong> Drteona.n@gmail.com<\/a><\/p>\n

Facebook : <\/strong>Endocrinologue Teona Nutsubidze<\/p>\n

LinkedIn :\u00a0 <\/strong>www.linkedin.com\/in\/teona-nutsubidze-560997201<\/a><\/p>","protected":false},"excerpt":{"rendered":"

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