{"id":126138,"date":"2024-06-27T18:07:31","date_gmt":"2024-06-27T17:07:31","guid":{"rendered":"https:\/\/easo.org\/?p=126138"},"modified":"2024-06-27T18:11:44","modified_gmt":"2024-06-27T17:11:44","slug":"meet-our-paediatric-coms-department-of-pediatrics-paracelsus-medical-university-austria","status":"publish","type":"post","link":"https:\/\/easo.org\/fr\/meet-our-paediatric-coms-department-of-pediatrics-paracelsus-medical-university-austria\/","title":{"rendered":"RENCONTREZ NOS COMS EN P\u00c9DIATRIE : D\u00e9partement de p\u00e9diatrie, Universit\u00e9 de m\u00e9decine Paracelsus, Autriche"},"content":{"rendered":"

Bienvenue, Professeur Weghuber. Veuillez pr\u00e9senter votre COM \u2013 pourriez-vous nous parler de votre \u00e9quipe et des services que votre COM offre aux patients ?<\/strong><\/p>\n

Notre \u00e9quipe p\u00e9diatrique COM comprend environ 50 professionnels, qui travaillent au sein de notre \u00e9quipe clinique et de notre laboratoire de recherche. Notre \u00e9quipe clinique multidisciplinaire comprend des p\u00e9diatres, un chirurgien p\u00e9diatrique, des di\u00e9t\u00e9ticiens, des psychologues, des travailleurs sociaux, des infirmi\u00e8res et des scientifiques du sport. Notre laboratoire de recherche comprend des scientifiques issus de divers domaines tels que la biologie, la chimie, la g\u00e9n\u00e9tique et les statistiques, ainsi que des membres de l'\u00e9quipe qui fournissent un soutien administratif.<\/p>\n

Notre COM offre une gamme compl\u00e8te de services aux patients, notamment des \u00e9valuations m\u00e9taboliques (avec tests g\u00e9n\u00e9tiques), des \u00e9valuations psychologiques et un soutien psychologique, des formations \u00e0 la modification du comportement, une pharmacoth\u00e9rapie et une r\u00e9\u00e9ducation en milieu hospitalier. Nous proposons \u00e9galement aux patients un suivi num\u00e9rique et des interventions chirurgicales, si n\u00e9cessaire. Notre \u00e9quipe de sp\u00e9cialistes prend fr\u00e9quemment en charge des cas complexes impliquant des patients souffrant d'ob\u00e9sit\u00e9 s\u00e9v\u00e8re et de complications de sant\u00e9 associ\u00e9es. Notre \u00e9quipe COM adopte une approche holistique de la prise en charge de l'ob\u00e9sit\u00e9, comprenant des \u00e9valuations approfondies, des interventions m\u00e9dicales et psychologiques, ainsi qu'une collaboration \u00e9troite avec les services sociaux et d'autres prestataires de soins de sant\u00e9 afin d'apporter un soutien complet aux patients et \u00e0 leurs familles.<\/p>\n

Votre COM participe-t-elle actuellement \u00e0 des projets de recherche ? Si oui, veuillez les d\u00e9crire bri\u00e8vement.<\/strong><\/p>\n

Oui, notre COM participe activement \u00e0 plusieurs projets de recherche ax\u00e9s sur les comorbidit\u00e9s m\u00e9taboliques, notamment le m\u00e9tabolisme du glucose et des graisses (en particulier, la sensibilit\u00e9 et la s\u00e9cr\u00e9tion perturb\u00e9es de l'insuline) et les ph\u00e9notypes de l'ath\u00e9roscl\u00e9rose pr\u00e9clinique. Les membres de notre COM explorent \u00e9galement la g\u00e9n\u00e9tique mitochondriale, ainsi que les interventions pharmacologiques et li\u00e9es au mode de vie chez les enfants et les adolescents souffrant d'ob\u00e9sit\u00e9. La pr\u00e9vention et l'\u00e9pid\u00e9miologie de l'ob\u00e9sit\u00e9 infantile sont d'autres domaines de recherche dans lesquels notre \u00e9quipe est impliqu\u00e9e. Notre groupe de recherche fait partie du centre de recherche YOUNG.HOPE pour la m\u00e9decine p\u00e9diatrique et adolescente, bas\u00e9 \u00e0 Salzbourg, en Autriche (http:\/\/www.younghope.at<\/a>), qui prend en charge les enfants atteints de troubles m\u00e9taboliques, notamment de troubles m\u00e9taboliques cong\u00e9nitaux et de maladies non transmissibles, ainsi que de troubles du d\u00e9veloppement et de troubles nutritionnels.<\/p>\n

Merci. Pouvez-vous nous faire part des actualit\u00e9s ou des points forts de la recherche men\u00e9e par votre COM au cours des derni\u00e8res ann\u00e9es ?<\/strong><\/p>\n

R\u00e9cemment, notre \u00e9quipe s'est consacr\u00e9e \u00e0 l'un de nos principaux domaines de recherche : les m\u00e9dicaments anti-ob\u00e9sit\u00e9 chez les adolescents ob\u00e8ses et leur application dans la pratique clinique. Plusieurs publications dans ce domaine nous ont donn\u00e9 une grande visibilit\u00e9 \u00e0 l'\u00e9chelle r\u00e9gionale, nationale et internationale. L'une des publications issues de ces travaux peut \u00eatre consult\u00e9e ici : Semaglutide administr\u00e9 une fois par semaine chez les adolescents souffrant d'ob\u00e9sit\u00e9 (Weghuber et al., 2022)<\/a>. Notre \u00e9tude a montr\u00e9 qu'une dose hebdomadaire de 2,4 mg de s\u00e9maglutide administr\u00e9e par voie sous-cutan\u00e9e r\u00e9duisait significativement l'IMC chez les adolescents ob\u00e8ses par rapport \u00e0 un placebo, en association avec une intervention sur le mode de vie, sur une p\u00e9riode de 68 semaines. Cependant, les effets secondaires gastro-intestinaux \u00e9taient plus fr\u00e9quents dans le groupe trait\u00e9 par s\u00e9maglutide, avec quelques cas de chol\u00e9lithiase et d'autres \u00e9v\u00e9nements ind\u00e9sirables graves. La disponibilit\u00e9 des m\u00e9dicaments anti-ob\u00e9sit\u00e9 a \u00e9t\u00e9 un facteur important dans le d\u00e9veloppement de la prise en charge globale de l'ob\u00e9sit\u00e9 ; l'int\u00e9gration des m\u00e9dicaments anti-ob\u00e9sit\u00e9 dans les strat\u00e9gies de prise en charge existantes a donn\u00e9 lieu \u00e0 de nouveaux concepts et \u00e0 des activit\u00e9s de recherche continues. Cet article pertinent a apport\u00e9 une contribution significative au travail de notre \u00e9quipe au cours de l'ann\u00e9e \u00e9coul\u00e9e : R\u00e9duction de l'IMC en dessous du seuil d'ob\u00e9sit\u00e9 chez les adolescents trait\u00e9s par 2,4 mg de s\u00e9maglutide sous-cutan\u00e9 une fois par semaine (Kelly et al., 2023)<\/a>. En outre, notre COM \u00e9tait un leader dans le domaine de la \u00e9laboration d'une strat\u00e9gie nationale de traitement de l'ob\u00e9sit\u00e9 infantile<\/a>, et met actuellement en place un centre d\u00e9di\u00e9 \u00e0 l'ob\u00e9sit\u00e9 infantile, juv\u00e9nile et adulte \u00e0 Salzbourg, qui vise \u00e0 int\u00e9grer les services de prise en charge de l'ob\u00e9sit\u00e9 tout au long de la vie.<\/p>\n

Cette \u00e9dition de l'initiative \u2018 Meet the COMs \u2019 (Rencontrez les COM) a mis \u00e0 l'honneur le COM p\u00e9diatrique du d\u00e9partement de p\u00e9diatrie de l'universit\u00e9 de m\u00e9decine Paracelsus en Autriche, dirig\u00e9 par le professeur Weghuber. Elle a mis en avant les services complets propos\u00e9s par ce COM en mati\u00e8re d'ob\u00e9sit\u00e9 infantile, ses projets de recherche en cours et ses d\u00e9couvertes importantes dans le domaine des m\u00e9dicaments anti-ob\u00e9sit\u00e9. Le professeur Weghuber a \u00e9galement pr\u00e9sent\u00e9 les r\u00e9sultats obtenus par le COM en mati\u00e8re de recherche et d'\u00e9laboration d'une strat\u00e9gie nationale de traitement. Merci, Dr Weghuber !<\/em><\/p>","protected":false},"excerpt":{"rendered":"

Welcome, Prof. Dr Weghuber. Please introduce your COM \u2013 could you tell us about your team and the services your COM offers to patients? Our paediatric COM team comprises around 50 professionals, who are positioned in our clinical team and in our research lab. 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